| 【所 属】 | 数理・推論研究系 統計基礎数理グループ | ![]() |
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| 【連 絡 先】 | E-mail : smano Home Page : http://www.ism.ac.jp/~smano/ | ||||||||||
| 【学 歴】 |
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| 【職 歴】 |
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| 【学 位】 |
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| 【専門分野】 | 数理遺伝学,統計遺伝学 | ||||||||||
| 【研究テーマ】 | 「集団遺伝の確率モデル」(ゲノム多様性の確率モデルによる推測) | ||||||||||
| 【論 文】 |
(1) Mano, S., Yasuda, N., Katoh, T., Tounai, K., Inoko, H., Imanishi, T., Tamiya, G., Gojobori, T. (2004): Notes on the maximum likelihood estimation of haplotype frequencies, Annals of Human Genetics 68, 257-264. (2) Mano, S. (2005): Random genetic drift and gamete frequency, Genetics 171, 2043-2050. (3) Tanaka, Y., Kurbanov, F., Mano, S., Orito, E., Vargas, V., Esteban, J.I., Yuen, M-F., Lai, C-L., Kramvis, A., Kew, M.C., Smuts, H.E.m Netesov, S.V., Alter, H.J., Mizokami, M. (2006): Molecular tracing of the grobal hepatits C virus epidemic predicts regional patterns of hepatocellular carcinoma mortality, Gastroenterology 130, 703-714. (4) Mano, S. (2007): Evolution of linkage disequilibrium of the founders in exponentially growing populations, Theoretical Population Biology 71, 95-108. (5) Zeng, K., Mano, S., Shi, S., Wu, C-I. (2007): Comparisons of site- and haplotype-frequency methods for detecting positive selection, Molecular Biology and Evolution 24, 1562-1574. (6) Mano, S., Innan, H. (2008): The evolutionary rate of duplicated genes under concerted evolution, Getetics 180, 493-505. (7) Mano, S. (2009): Duality, ancestral and diffusion processes in models with selection, Theoretical Population Biology 75, 164-175. (8) Mano, S., Endo, T.A., Oka, A., Ozawa, A., Gojobori, T., Inoko, H. (2009): Detecting linkage between a trait and a marker in a random mating population without pedigree record, PLoS One 4, e4956. (9) Osada, N., Mano, S,., Gojobori, J. (2009): Quantifying dominance and deleterious effect on human disease genes, Proceedings of the National Academy of Science, USA 106, 841-846. (10) Nakagome, S., Takeyama, Y., Mano, S., Sakisaka, S., Matsui, T., Kawamura, S., Oota, H. (2010): Population-specific susceptibility to Crohn's disease and ulcerative colitis; Dominant and recessive relative risks in the Japanese population, Annals of Human Genetics 74, 126-136. | ||||||||||
| 【学 会】 | 日本遺伝学会,日本計量生物学会,日本進化学会,日本人類遺伝学会,日本数理生物学会,日本統計学会 | ||||||||||
| 【所外における活動】 | Journal of Theoretical Biology(Editorial Board, 2010年-) | ||||||||||